Status:

COMPLETED

Serum Uromodulin and DN Systematic Review and Meta Analysis

Lead Sponsor:

Tanta University

Collaborating Sponsors:

Ain Shams University

Conditions:

Diabetic Nephropathies

Eligibility:

All Genders

Brief Summary

Several studies have investigated the association between the changes of serum uromodulin and diabetic nephropathy (DN). However, the results are still controversial. Hence, this meta-analysis aimed t...

Eligibility Criteria

Inclusion

  • Studies were included if they met the following criteria:
  • serum level of uromodulin was determined;
  • the samples were enrolled from diabetic patients;
  • mean ± SD was reported for uromodulin between patients with and without DN;
  • the level of albumin to creatinine ratio (ACR), glomerular filtration rate (GFR), or albumin excretion rate (AER) in patients with DN was determined

Exclusion

  • Studies were excluded according to the following criteria:
  • duplicate studies;
  • review articles;
  • non original research articles;
  • studies with insufficient data to extract;
  • non-human research;
  • studies that determined urine level of uromodulin.

Key Trial Info

Start Date :

May 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 30 2024

Estimated Enrollment :

1774 Patients enrolled

Trial Details

Trial ID

NCT06596863

Start Date

May 1 2024

End Date

May 30 2024

Last Update

September 19 2024

Active Locations (1)

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Tanta Yniversity

Tanta, Yes, Egypt, 31511