Status:

ACTIVE_NOT_RECRUITING

BIOMARKER and IMAGING CHARACTERISATION of INFLAMMATORY ATHEROMA in PATIENTS RECEIVING IMMUNOTHERAPY and ANGIOGENESIS INHIBITORS

Lead Sponsor:

NHS Greater Glasgow and Clyde

Collaborating Sponsors:

Roche Diagnostics GmbH

University of Glasgow

Conditions:

Cancer

Cardiotoxicity

Eligibility:

All Genders

18+ years

Brief Summary

The advent of immunotherapy (immune checkpoint inhibitors \[ICI\]) has been an extremely important advancement for cancer treatment in recent decades. The anti-cancer effects of these agents is profou...

Eligibility Criteria

Inclusion

  • Patients with cancer who are planned for treatment with ICI or VEGFI, including combination therapy
  • ≥6 months predicted survival
  • Age ≥18 years

Exclusion

  • Patients who are unable or unwilling to provide valid consent for the study
  • Patients with diabetes who are on oral anti-diabetic treatment or insulin at baseline
  • patients who have exposure to either immune checkpoint inhibitor or VEGF inhibitor in the 12 months before enrolment

Key Trial Info

Start Date :

August 30 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 20 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06597045

Start Date

August 30 2022

End Date

November 20 2024

Last Update

September 19 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Beatson West of Scotland Cancer Centre

Glasgow, United Kingdom, G120YN