Status:

RECRUITING

Beetroot Juice: A Natural Boost for Cardiovascular Health in Postmenopausal Women?

Lead Sponsor:

Western Norway University of Applied Sciences

Conditions:

Post-menopause

Eligibility:

FEMALE

Up to 65 years

Phase:

NA

Brief Summary

This study aims to explore the effects of short-term beetroot juice (BRJ) supplementation on cardiovascular health in post-menopausal women. The primary focus is to determine whether BRJ, rich in nitr...

Detailed Description

This study aims to evaluate the short-term effects of beetroot juice (BRJ) supplementation on blood pressure and oxygen uptake during exercise in post-menopausal women. Post-menopausal women are at in...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Females under the age of 65
  • Self-reported absence of menstrual cycle for \>1 year
  • BMI \<30 kg/m2.
  • Able to walk on a treadmill and cycle on a stationary bike without problems.
  • Proficient in Norwegian and able to provide informed consent.
  • Exclusion criteria:
  • Current or recent (last 5 years) regular smoker or user of nicotine products
  • Addictions to alcohol or illegal drugs
  • Allergy or intolerance (s) to nitrate or BRJ supplement.
  • Diagnosed with cardiovascular disease (e.g., previous acute myocardial infarction or stroke, peripheral artery disease, heart failure), renal, or respiratory (e.g., asthma, sleep apnea).
  • Regular usage of nitrate supplements, including beetroot juice
  • Hormone replacement therapy.
  • Uncontrolled high blood pressure (e.g., resting systolic and diastolic blood pressure \>160/110 mmHg)
  • Problems with very low blood pressure (e.g., severe dizziness upon standing)
  • Diagnosed with diabetes (type 1 or type 2).
  • Using blood pressure or glucose-lowering medications
  • Close family (parents, siblings, children) history of sudden cardiac death at an early age (\<55 for men, \<65 for women)
  • Judgment by a medical provider that exercise poses an undue burden or risk.
  • Cognitive or psychiatric impairment
  • Lack of proficiency in Norwegian language oral or writing skills that will hamper the ability to participate in the interventions and fill out questionnaires.

Exclusion

    Key Trial Info

    Start Date :

    September 2 2024

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    January 1 2028

    Estimated Enrollment :

    20 Patients enrolled

    Trial Details

    Trial ID

    NCT06598488

    Start Date

    September 2 2024

    End Date

    January 1 2028

    Last Update

    September 19 2024

    Active Locations (1)

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    Western Norway University of Applied Sciences

    Bergen, Norway, 5063