Status:

NOT_YET_RECRUITING

Perfusion Abnormalities in Hypertrophic Cardiomyopathy

Lead Sponsor:

University of Virginia

Conditions:

Hypertrophic Cardiomyopathy (HCM)

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to investigate whether myocardial microvascular perfusion in patients with hypertrophic cardiomyopathy improved after initiation of cardiac myosin inhibitor therapy.

Eligibility Criteria

Inclusion

  • Diagnosis of hypertrophic cardiomyopathy
  • Subject being initiated on clinically-indicated cardiac myosin inhibitor therapy

Exclusion

  • Pregnancy
  • Lactation
  • Allergy to ultrasound enhancing agent (lipid-stabilized) or regadenoson
  • Serious AE to regadenoson
  • Hypotension
  • Serious bradycardia not addressed by pacemaker
  • Moderate or greater reactive airways disease

Key Trial Info

Start Date :

November 15 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2028

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06599229

Start Date

November 15 2024

End Date

December 1 2028

Last Update

September 19 2024

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Perfusion Abnormalities in Hypertrophic Cardiomyopathy | DecenTrialz