Status:

COMPLETED

Efficacy Assessment of Lenvatinib Associated with Pembrolizumab in Metastatic Endometrial Cancer: a French Multicentric Retrospective Early Access Program-based Study

Lead Sponsor:

ARCAGY/ GINECO GROUP

Collaborating Sponsors:

Institut Curie

Conditions:

Metastatic Endometrial Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

LARENA is a multicentric retrospective study (secondary use of data) of consecutive patients prospectively registered in the lenvatinib plus pembrolizumab French early access program (Temporary Author...

Eligibility Criteria

Inclusion

  • Patients having received at least one dose of lenvatinib plus pembrolizumab in the context of the French early access program (Temporary Authorisation for Use) approved by the French Health Autority.
  • Patients with advanced or recurrent endometrial cancer whose disease is progressing during or following prior platinum-based chemotherapy at any stage and who are not eligible for curative surgery or radiotherapy, according to the French early access program (Temporary Authorisation for Use) approved by the French Health Autority criteria.

Exclusion

  • Patients who refuse the collection and use of their personal data in the course of this research.

Key Trial Info

Start Date :

August 19 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2025

Estimated Enrollment :

351 Patients enrolled

Trial Details

Trial ID

NCT06599463

Start Date

August 19 2024

End Date

February 28 2025

Last Update

March 20 2025

Active Locations (24)

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Page 1 of 6 (24 locations)

1

ICO Paul Papin

Angers, France, 49055

2

Sainte Catherine - Institut du Cancer Avignon

Avignon, France, 84918

3

CHU Jean Minjoz

Besançon, France, 25000

4

ICONE

Bezannes, France, 51430