Status:
COMPLETED
PET/CT-Based Image Analysis and Machine Learning of Hypermetabolic Pulmonary Lesions
Lead Sponsor:
Ruijin Hospital
Collaborating Sponsors:
Shanghai Pulmonary Hospital, Shanghai, China
Jiangsu Province Hospital of Traditional Chinese Medicine
Conditions:
Lung Cancers
Pulmonary Lymphomas
Eligibility:
All Genders
18+ years
Brief Summary
First, we analyse the types, imaging findings and relevant treatment responses based on PET/CT to complete a more comprehensive view of pulmonary lymphomas. Then, some models based on radiomics featu...
Detailed Description
1. The local image feature extraction software (LIFEx, v 7.4.0, France) was employed for the image review and measurement of relevant data. Three observers independently interpreted the images. In cas...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Adult patients (≥18 years);
- Primary or recurrent lymphoma, ≥6 months from last treatment; primary lung cancer patients without prior malignancy;
- Benign solid lung lesions, without prior malignancy;
- Pulmonary metastasis, untreated with lung radiotherapy or particle implantation;
- Baseline assessment revealing PET-positive pulmonary lesions.
- Pathological results within 3 months of exam date, confirmed lung lesion types via tracheoscopy, lung puncture, or surgery.
- Baseline pulmonary lesions remaining considered to be pulmonary lymphoma (or metastases) based on follow-up clinical and imaging evaluation.
- Exclusion criteria:
- Poor image quality;
- Inability to delineate the boundaries of lung lesions on CT images;
- Artifacts caused by nearby devices such as stents or drainage tubes.
Exclusion
Key Trial Info
Start Date :
April 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 30 2025
Estimated Enrollment :
647 Patients enrolled
Trial Details
Trial ID
NCT06602674
Start Date
April 1 2024
End Date
April 30 2025
Last Update
July 23 2025
Active Locations (1)
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1
Ruijin Hospital affiliated to Shanghai Jiao Tong University of Medicine
Shanghai, Shanghai Municipality, China, 200025