Status:
COMPLETED
The Effects of Nitrate, Caffeine, and Cold Exposure on Cardiovascular Function.
Lead Sponsor:
Loughborough University
Collaborating Sponsors:
Biogen Extracts Pvt Ltd
Conditions:
Nitrate
Caffeine
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Dietary inorganic nitrate supplementation may have positive implications on cardiovascular function. The aim of this project is to determine if nitrate supplementation can attenuate the effects that c...
Detailed Description
Acute caffeine consumption and cold exposure elicit negative effects on the cardiovascular system. Humans are regularly exposed to such conditions of increased cardiovascular strain, which may lead to...
Eligibility Criteria
Inclusion
- Blood pressure \< 130 mmHg systolic and \< 85 mmHg diastolic. BMI between 18.5 and 29.9 kg/m2. Females must be naturally menstruating (regular length cycle and menses) or using a form of combined hormonal contraception (for at least 6 months).
Exclusion
- Existing cardiovascular or metabolic conditions. Experience any adverse reactions to experimental procedures or supplements. Allergies to supplements or breakfast items. Involved in any other studies. Blood pressure \> 130 mmHg systolic and \> 85 mmHg diastolic.
Key Trial Info
Start Date :
December 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2025
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06602921
Start Date
December 5 2023
End Date
April 1 2025
Last Update
September 12 2025
Active Locations (1)
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1
Loughborough University
Loughborough, United Kingdom, LE11 3TU