Status:

NOT_YET_RECRUITING

Role of Serum (B/A) Ratio Compared to (TSB) for Early Prediction of Bilirubin-induced Neurological Dysfunction (BIND).

Lead Sponsor:

alaa aboelhassan mohamed aboelhassan

Conditions:

Hyperbilirubinemia, Neonatal

Eligibility:

All Genders

1-28 years

Brief Summary

The aim of this study is to evaluate serum bilirubin/albumin (B/A) ratio compared to total serum bilirubin (TSB) for early prediction of bilirubin-induced neurological dysfunction (BIND).

Detailed Description

Introduction Neonatal hyperbilirubinemia is a common problem in neonates. Approximately 60% of term and 80% of preterm babies develop jaundice in the first week of life and about 10% of breastfed babi...

Eligibility Criteria

Inclusion

  • • Neonates with hyperbilirubinemia reached level of phototherapy or exchange transfusion according to the American Academy of Pediatrics guidelines \[14\].
  • Age: from 1 to 28 day.
  • Full term and preterm babies.
  • Both sexes.

Exclusion

  • Conjugated hyperbilirubinemia.
  • Perinatal asphyxia.
  • Patients with encephalopathy due to causes other than hyperbilirubinemia.
  • Severe birth defects or congenital anomalies.
  • Hemodynamic instability.
  • Septic patients.

Key Trial Info

Start Date :

January 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2026

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06603753

Start Date

January 1 2025

End Date

July 1 2026

Last Update

September 19 2024

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