Status:
RECRUITING
Anesthesia Induction Scheme for Painless Gastrointestinal Endoscopy Patients Based on Nociceptive Stimulation Monitoring
Lead Sponsor:
Min Su
Conditions:
Depth of Anesthesia
Nociception
Eligibility:
All Genders
18-60 years
Brief Summary
Nociception is the encoding and processing of noxious stimulation and is considered an objective indicator for monitoring pain. Currently, a new clinically-applied medical-engineering integrated monit...
Detailed Description
This is a single-center, prospective, observational clinical study. Study Objective: To explore the optimal sedation quality for painless gastrointestinal endoscopy. Study Protocol: A total of 220 pat...
Eligibility Criteria
Inclusion
- Aged 18-60 years old;
- American Society of Anesthesiologists (ASA) Class I-III;
- Body mass index (BMI): 18-30 kg/m\^2;
- Individuals scheduled for elective gastroscopy and colonoscopy examinations;
- Willing to comply with the experimental procedures and voluntarily sign the informed consent form
Exclusion
- Pregnant or breastfeeding women;
- Individuals with allergies to sedatives/anesthetic drugs or other severe anesthetic risks;
- Patients with chronic preoperative pain or a history of substance abuse;
- Individuals with severe neurological diseases, such as stroke, hemiplegia, seizures, epilepsy, etc.;
- Patients with clearly difficult airways, such as those with limited mouth opening, neck or jaw mobility restrictions, rheumatoid arthritis, or temporomandibular joint disorders;
- Individuals with respiratory diseases, such as bronchitis, asthma, chronic obstructive pulmonary disease, or acute respiratory infections, which may lead to increased airway sensitivity;
- Patients with chronic pharyngitis, laryngitis, laryngeal edema, or recurrent laryngeal nerve paralysis that may affect normal throat function;
- Individuals with esophagitis, esophageal strictures, or esophageal motility disorders that may cause difficulty swallowing or reflux;
- Patients with poorly controlled life-threatening cardiovascular diseases, such as uncontrolled severe hypertension, severe arrhythmias, or unstable angina; 10.10.Patients with liver dysfunction (Child-Pugh grade C or above), acute upper gastrointestinal bleeding with shock, severe anemia, or gastrointestinal obstruction with retained gastric contents.
Key Trial Info
Start Date :
September 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 31 2025
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT06604156
Start Date
September 1 2024
End Date
October 31 2025
Last Update
March 6 2025
Active Locations (1)
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1
China,Chongqing The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China, 400016