Status:
COMPLETED
Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery
Lead Sponsor:
Afyonkarahisar Health Sciences University
Conditions:
Wisdom Teeth
Edema Face
Eligibility:
All Genders
18-25 years
Phase:
PHASE4
Brief Summary
The aim of this study is to comparatively evaluate the effects of dexamethasone injected into the masseter muscle and pterygomandibular space after mandibular third molar surgery on postoperative pain...
Detailed Description
Our study aims to reduce pain, edema and restricted mouth opening (trismus) that are frequently seen after impacted tooth extraction operations with steroid applied locally to the area where the opera...
Eligibility Criteria
Inclusion
- 1\. Patients with no systemic disease, AAD (American Society of Anesthesiologists) class I and BMI (body mass index) below 30.
- 2\. Patients between the ages of 18-25 with bilaterally symmetrical and mesioangularly positioned impacted third molars in the mandible.
- 3\. Patients with impacted mandibular third molars in class II-B according to the Pell and Gregory classification.
- 4\. Patients with impacted third molars that are fully or partially retained and asymptomatic.
- 5\. Patients with impacted mandibular third molars that are not associated with any pathology such as cysts or tumors and do not have active perichronitis.
- 6\. Patients with at least 2/3 of root development completed.
- 7\. Patients without complaints such as active caries, periodontal disease, pain or swelling in the operation area.
- 8\. Patients without a history of infection or perichronitis in the operation area.
Exclusion
- 1\. Patients with a history of allergy to dexamethasone or other drugs to be used in the study.
- 2\. Patients with systemic bacterial, viral, and fungal infections.
- 3\. Breastfeeding mothers.
- 4\. Patients with diagnosed or suspected pregnancies.
- 5\. Patients in whom corticosteroids are contraindicated.
- 6\. Patients who have recently been treated with anti-inflammatory drugs.
- 7\. Patients with cardiovascular disease.
- 8\. Patients with acute or chronic maxillary sinusitis.
- 9\. Patients who are taking medications such as antidepressants or antihistamines on a regular basis.
- 10\. Patients with psychiatric problems.
- 11\. Patients with diabetes mellitus, rheumatic diseases, hematological diseases, or liver diseases.
- 12\. Patients at risk of effective endocarditis.
- 13\. Patients who smoke.
- 14\. Patients who use oral contraceptives.
Key Trial Info
Start Date :
April 28 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 27 2024
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06604286
Start Date
April 28 2023
End Date
April 27 2024
Last Update
September 20 2024
Active Locations (1)
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1
Afyonkarahisar Health Sciences University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery
Afyonkarahisar, Afyonkarahisar, Turkey (Türkiye), 03030