Status:
RECRUITING
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
Lead Sponsor:
University of Illinois at Urbana-Champaign
Conditions:
Cognitive Change
Diet, Healthy
Eligibility:
All Genders
45-64 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a h...
Detailed Description
The purpose of this study is to understand how a healthy diet is related to thinking ability and heart health. Participants will be asked to consume a microwaveable study meal or prepackaged smoothie ...
Eligibility Criteria
Inclusion
- 45-64 years of age
- 20/20 or corrected vision
- No food allergies or intolerances
- Not pregnant, lactating, or have given birth in the past 12 months
- Do not smoke, use tobacco, or abuse drugs
- Absence of liver or gastrointestinal diseases (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, and cancer
- Not currently taking oral hypoglycemic agents, or insulin
- No history of malabsorptive or bariatric surgery
- Cognitively intact with no prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and/or Asperger's syndrome)
- Able to consume the study meals
- Not enrolled in another dietary, exercise, or medication study during the study.
Exclusion
- Non-consent of participant
- Above 64 or below 45 years of age
- Vision not 20/20 or corrected
- Food allergies or intolerances
- Pregnant, lactating, or have given birth in the past 12 months
- Smoke, use tobacco, or abuse drugs
- Prior diagnosis of liver or gastrointestinal disease (i.e., primary biliary cirrhosis or gallbladder disease, chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers), hepatitis, HIV, or cancer
- Currently taking oral hypoglycemic agents or insulin
- History of malabsorptive or bariatric surgery
- Cognitively impaired and/or prior diagnosis of neurological disease (i.e., mild cognitive impairment, Alzheimer's disease, vascular dementia, and/or Asperger's syndrome)
- Unable to consume the study meals
- Concurrent enrollment in another dietary, exercise, or medication study
Key Trial Info
Start Date :
July 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT06605898
Start Date
July 3 2024
End Date
December 31 2027
Last Update
September 20 2024
Active Locations (1)
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1
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States, 61801