Status:

COMPLETED

Assessment of the Efficacy of Topical Curcumin in Treatment of Oral Lichen Planus

Lead Sponsor:

Shaymaa Hussein Rafat Kotb

Conditions:

Oral Lichen Planus

Eligibility:

All Genders

20-70 years

Phase:

PHASE3

Brief Summary

to evaluate the therapeutic impact of curcumin as Alternative or Complementary to Triamcinolone Acetonate in Treatment of Oral Lichen Planus.

Detailed Description

Background: Oral lichen planus (OLP) is a chronic inflammatory disorder affecting the mucous membranes, believed to be an immune-mediated condition. Its persisting nature can lead to extended discomfo...

Eligibility Criteria

Inclusion

  • clinical diagnosis of OLP

Exclusion

  • Any systemic autoimmune disease
  • Any current use of anticoagulant or antiplatelet agents (curcumin has inhibitory effects on platelet aggregations).
  • Any topical, local or systemic corticosteroids therapy during the past 3 months.
  • lichenoid reaction from medications.
  • Pregnant or lactation women.
  • smokers

Key Trial Info

Start Date :

June 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06605911

Start Date

June 1 2023

End Date

June 1 2024

Last Update

September 20 2024

Active Locations (1)

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Al-Azhar university

Asyut, Ass, Egypt, 0000