Status:
RECRUITING
Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
Haystack Oncology, Inc.
Conditions:
Squamous Cell Carcinoma of Head and Neck
Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
Eligibility:
All Genders
18+ years
Brief Summary
This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinoma...
Detailed Description
PRIMARY OBJECTIVE: I. To determine the rates of detectable ctDNA within two years of participants treated with curative-intent surgery or radiation-based treatment for HNC. SECONDARY OBJECTIVES: 1....
Eligibility Criteria
Inclusion
- Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
- Participants must be age \>=18 years.
- Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of standard of care treatment.
- Participants must have the ability to understand and the willingness to sign a written informed consent document.
Exclusion
- 1\. Contraindication to phlebotomy for removal of 20 mL of peripheral blood each time point (up to 300 mL total over 15 time points).
Key Trial Info
Start Date :
October 9 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2029
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT06606028
Start Date
October 9 2024
End Date
December 30 2029
Last Update
December 12 2025
Active Locations (1)
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1
University of California, San Francisco
San Francisco, California, United States, 94143