Status:

COMPLETED

Neuropeptide Y Regulates Neurogenic Pulp Inflammation

Lead Sponsor:

Institucion Universitaria Colegios de Colombia

Conditions:

Neurogenic Inflammation

Dental Pulp Disease

Eligibility:

All Genders

18-27 years

Phase:

NA

Brief Summary

Objective. This study assessed the neuropeptide Y (NPY) expression in healthy human dental pulp following tooth bleaching with three in-office hydrogen peroxide-based systems: Opalescence Boost© (Ultr...

Eligibility Criteria

Inclusion

  • Dental pulps were collected from non-smoking donors
  • Patients who need premolar extractions for orthodontic purposes.
  • These premolars must meet the following requirements:
  • Caries and restoration-free,
  • Complete root development (visually and radiographically confirmed),
  • Normal response to sensitivity testing.

Exclusion

  • Evidence of periodontal disease,
  • Traumatic occlusion
  • Previous orthodontic force application.

Key Trial Info

Start Date :

February 5 2024

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 28 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06606236

Start Date

February 5 2024

End Date

February 28 2024

Last Update

September 23 2024

Active Locations (1)

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1

Facultad de Odontologia, Unicoc

Bogotá, Colombia