Status:

COMPLETED

Immunohistochemical Expression of EGFR in the Patients Having Oral Squamous Cell Carcinoma

Lead Sponsor:

Combined Military Hospital, Pakistan

Collaborating Sponsors:

National University of Medical Sciences, Pakistan

Conditions:

Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer

Eligibility:

All Genders

Brief Summary

Oral squamous cell carcinoma (OSCC) is one of the top 10 most common malignancies worldwide. Oral squamous cell carcinoma forms a major health problem in many countries. The reason for the high incide...

Detailed Description

Oral SCC is a type of cancer that develops from the oral epithelium and accounts for more than 90% of all oral malignancies, with a death rate of more than 140,000 cases globally. It is an invading ne...

Eligibility Criteria

Inclusion

  • Cases of surgically treated lip/oral cavity squamous cell carcinoma
  • Patients of all age groups, irrespective of their gender
  • Patients with a tumor located in the tongue, inferior and superior gingivae, buccal mucosa, floor of the mouth, palate, alveolus and vestibule(buccal/labial and mandible/maxilla)

Exclusion

  • All specimens with inadequate or poor fixation.
  • All specimen of patients having received chemotherapy/radiotherapy prior to surgery
  • Very scanty tissue biopsies or those with extensive tissue necrosis
  • Patients not consenting to be the part of the study

Key Trial Info

Start Date :

August 26 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 28 2023

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT06606301

Start Date

August 26 2023

End Date

December 28 2023

Last Update

September 24 2024

Active Locations (1)

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1

Armed Forces Institute of Pathology, Combined Military Hospital

Rawalpindi, Punjab Province, Pakistan, 46000