Status:

RECRUITING

ENDO-BRAIN: Effects of Endocrine Adjuvant Therapy with Aromatase Inhibitors on the Cognitive Function of Breast Cancer Patients

Lead Sponsor:

Ospedale Policlinico San Martino

Collaborating Sponsors:

University of Genova

Conditions:

Cognitive Side Effects of Cancer Therapy

Hypoestrogenism

Eligibility:

FEMALE

18+ years

Brief Summary

The principal aim of this prospective observational study is to investigate the cognitive function of breast cancer patients that use AI, comparing it with age-matched healthy controls, utilizing cogn...

Eligibility Criteria

Inclusion

  • Breast cancer patients undergoing endocrine adjuvant therapy with AI, with or without GnRH agonists, depending on menopause status at diagnosis (cases only)
  • At least 18 years old
  • Good comprehension of oral and written Italian language

Exclusion

  • incomplete ovarian suppression (cases)
  • previous neoplastic diseases other than the presently treated breast cancer for cases
  • known neurological or psychiatric disorders
  • use of hormonal contraception or hormonal replacement therapy (controls)

Key Trial Info

Start Date :

June 13 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06606535

Start Date

June 13 2024

End Date

June 1 2025

Last Update

September 23 2024

Active Locations (1)

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IRCCS Ospedale Policlinico San Martino

Genova, GE, Italy, 16132

ENDO-BRAIN: Effects of Endocrine Adjuvant Therapy with Aromatase Inhibitors on the Cognitive Function of Breast Cancer Patients | DecenTrialz