Status:

NOT_YET_RECRUITING

FMT for Insomnia Disorder (FMT-SLEEP)

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Chronic Insomnia Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Insomnia disorder is characterized by difficulty initiating or maintaining sleep, or early morning awakening accompanied by symptoms such as irritability or fatigue during wakefulness. It is one of th...

Detailed Description

Insomnia disorder is characterized by difficulty initiating or maintaining sleep, or early morning awakening accompanied by daytime symptoms such as irritability or fatigue. It is one of the most prev...

Eligibility Criteria

Inclusion

  • 1\. Individuals aged 18 and above
  • 2\. Subjects who were diagnosed with chronic insomnia disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and with moderate or above insomnia disorder defined as ISI \> 14

Exclusion

  • 1\. Having an additional sleep disorder, such as restless legs syndrome, or circadian rhythm sleep disorder, that can significantly disrupt the sleep cycle as ascertained by Diagnostic Interview for Sleep Patterns and Disorders (DISP)
  • 2\. Requiring immediate psychiatric care (e.g., imminently suicidal subjects) or have attempted suicide in the past 6 months
  • 3\. Change of treatment or therapy for insomnia within 4 weeks
  • 4\. Known history of severe organ failure (including decompensated cirrhosis), renal failure on dialysis, suffering from human immunodeficiency virus infection
  • 5\. Confirmed active malignancy
  • 6\. Had abdominal surgery
  • 7\. Contraindications to GI endoscopy
  • 8\. On shift work
  • 9\. Taking antibiotics, probiotic or prebiotic preparations within 4 weeks
  • 10\. Known pregnancy
  • 11\. Mental retardation or inability to provide informed consent
  • 12\. Are participating in other interventional studies

Key Trial Info

Start Date :

November 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2027

Estimated Enrollment :

74 Patients enrolled

Trial Details

Trial ID

NCT06606938

Start Date

November 1 2024

End Date

April 30 2027

Last Update

September 23 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Prince of Wales Hospital

Hong Kong, Hong Kong