Status:

RECRUITING

Opioid-free Anesthesia Protocol for Neurosurgical Supratentorial Tumor Resection

Lead Sponsor:

Beijing Tiantan Hospital

Conditions:

Supratentorial Tumors

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Opioids have many side effects, such as constipation, urinary retention, itchy skin, respiratory depression, and postoperative nausea and vomiting. These side effects can lead to delayed recovery, lon...

Detailed Description

Data sharing plan: The deidentified participant data reported in this study could be made available to researchers upon approval by the corresponding author (Dr. Ruquan Han, ruquan.han@ccmu.edu.cn) im...

Eligibility Criteria

Inclusion

  • Scheduled to undergo craniotomy for supratentorial tumors with general anesthesia;
  • 18 years≤age≤65 years;
  • American Society of Anesthesiologists (ASA) physical status of I to III;
  • Signed informed consent.

Exclusion

  • Patients with a body mass index (BMI)≥35 kg/m2;
  • Patients with severe hepatic and renal insufficiency;
  • Patients with cognitive dysfunction, aphasia and other states that do not cooperate with the assessment;
  • Preoperative magnetic resonance imaging of the head showed midline displacement \>5 mm;
  • Patients undergoing electrophysiological monitoring during surgery;
  • Pregnant or lactating patients.

Key Trial Info

Start Date :

October 21 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2026

Estimated Enrollment :

170 Patients enrolled

Trial Details

Trial ID

NCT06607029

Start Date

October 21 2024

End Date

March 31 2026

Last Update

March 11 2025

Active Locations (1)

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Beijing Tiantan Hospital

Beijing, China