Status:
RECRUITING
Glucagon-like Peptide-1 Receptor Agnoists for the Assessment of Adrenal Function
Lead Sponsor:
University Hospital, Basel, Switzerland
Conditions:
Healthy Volunteer Study
HPA
Eligibility:
MALE
18-60 years
Phase:
NA
Brief Summary
This study aims to investigate the effects of a single dose of the glucagon-like 1 receptor agonist semaglutdie/Rybelsus on the hypothalamo-pituitary-adrenal axis, thus cortisol levels and other stres...
Eligibility Criteria
Inclusion
- Healthy male volunteers aged 18-60 years
- BMI 18.5-30 kg/m2
- No regular medication
Exclusion
- participation in a trial with investigational drugs within 30 days
- vigorous physical exercise within 24 hours before the study participation
- alcohol intake within 24 hours before the study participation
- a history of intake of glucocorticoids or GLP-1 RA within the last 8 weeks.
- Known allergy towards GLP-1 RA
Key Trial Info
Start Date :
January 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2025
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT06608433
Start Date
January 16 2025
End Date
August 31 2025
Last Update
February 11 2025
Active Locations (1)
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1
University Hospital Basel
Basel, Switzerland