Status:
NOT_YET_RECRUITING
EMR Versus CSP in the Treatment of Sessile Serrated Lesions Less Than 10mm in Size
Lead Sponsor:
Fudan University
Conditions:
Colorectal Sessile Serrated Lesion
Eligibility:
All Genders
35-75 years
Phase:
NA
Brief Summary
A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of endoscopic mucosal resection (EMR) and cold snare polypectomy (CSP) in treating colorec...
Detailed Description
1. Patients are undergone screening, surveillance, or therapeutic colonoscopy at the Endoscopy department of Gastrointestinal endoscopy center of Huadong hospital affiliated to Fudan University. 2. Ra...
Eligibility Criteria
Inclusion
- Aged between 35 and 75 years
- Suspected sessile serrated lesions less than 10mm in size in screening, surveillance or therapeutic colonoscopy
- 0-Is or 0-IIa according to Paris classification
- Type 1 according to NICE and JNET classification
- Type II according to pit pattern
- Patients must sign an informed consent form prior to registration in study
Exclusion
- Unsuitable for removal by EMR or CSP
- Suspected dysplasia or malignancy
- Recurrent sessile serrated lesions after endoscopic resection
- Familial adenomatous polyposis, Lynch syndrome or serrated polyposis syndrome
- History of inflammatory bowel disease
- Patients taking anticoagulant and antiplatelet agents before the examination
- Severe illness or other high-risk conditions that prevent the patient from cooperating with or tolerating endoscopic therapy
- Refusal to sign the informed consent form or any other factors that are not suitable for enrollment or affect the ability to participate in the study
Key Trial Info
Start Date :
October 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
270 Patients enrolled
Trial Details
Trial ID
NCT06609031
Start Date
October 1 2024
End Date
October 1 2026
Last Update
September 25 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Huadong hospital affiliated to Fudan university
Shanghai, China, 200040