Status:
RECRUITING
Personalized Ultrasound-Guided External Diaphragm Pacing to Improve Outcomes in Invasive Mechanically Ventilated Patients
Lead Sponsor:
Daishan Jiang
Conditions:
Respiratory Failure
Mechanical Ventilation
Eligibility:
All Genders
18-95 years
Phase:
NA
Brief Summary
This study aims to explore whether personalized external diaphragm pacing (EDP) guided by real-time diaphragm ultrasound (DU) can improve outcomes for patients on invasive mechanical ventilation. Diap...
Detailed Description
This study investigates the efficacy of a personalized external diaphragm pacing (EDP) protocol, dynamically guided by diaphragm ultrasound (DU), in improving outcomes in mechanically ventilated patie...
Eligibility Criteria
Inclusion
- Adults ≥18 years of age undergoing invasive mechanical ventilation.
- Expected duration of mechanical ventilation ≥48 hours.
Exclusion
- ICU expected length of stay less than 48 hours
- severe phrenic nerve or diaphragmatic injury that is unable to respond to diaphragmatic pacing.
- Patients who have received or are scheduled to receive other respiratory assistance or diaphragmatic pacing interventions.
- Patients with end-stage disease with an expected survival of \<6 months.
- Patients who are unable to be weaned from mechanical ventilation, such as patients with severe brain injury or paraplegia.
Key Trial Info
Start Date :
November 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT06609577
Start Date
November 1 2024
End Date
August 31 2027
Last Update
October 22 2024
Active Locations (1)
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1
Affiliated Hospital of Nantong University
Nantong, Jiangsu, China, 226001