Status:

COMPLETED

Evaluation of the Effect of Circadian Rhythm of Adrenal Glucocorticoids After Third Molar Extraction

Lead Sponsor:

Afyonkarahisar Health Sciences University

Conditions:

Wisdom Teeth

Eligibility:

All Genders

18-25 years

Brief Summary

This study aimed to investigate the effects of wisdom tooth surgery performed at different times of the day on pain, swelling and trismus based on changes in the circadian rhythm in the adrenal glands...

Detailed Description

This clinical study was conducted on 20 patients who applied to the Afyonkarahisar Health Sciences University (AFSU) Faculty of Dentistry, Department of Oral and Maxillofacial Surgery between November...

Eligibility Criteria

Inclusion

  • Patients with bilateral wisdom teeth in the lower jaw and similar impacted positions
  • Patients with no history of trauma to the head and neck region, no congenital deformities, no degenerative joint disease, patients between the ages of 18 and 25,
  • Patients who have not received any treatment for the adrenal gland in the last 6 months, patients who have not used antidepressant medication in the last 6 months, patients who have no cardiovascular disease, thyroid disease, diabetes, hypertension, renal failure, isolated muscle disease, rheumatological and neurological disease, and patients who have no known psychiatric disorder,
  • Patients with good oral hygiene,
  • Patients who can comply with the scales in the questionnaire form,
  • Patients who have not had surgery on their lower wisdom teeth before,
  • Patients who have not used corticosteroids and anticonvulsant drugs,
  • Patients who have no active caries and pulpal lesions,
  • Patients who can fill out the questionnaire forms on their own. 10) Patients who have not received radiotherapy in the head and neck region and who do not use drugs that may cause MRONJ.

Exclusion

  • Patients who had undergone surgical treatment for their wisdom teeth before the study,
  • Patients with serious systemic diseases and those taking medication,
  • Pregnant and breastfeeding women,
  • Individuals using removable dentures,
  • Those receiving psychiatric treatment and those taking medication,
  • 7\. Those with a history of heart infarction, 8. Patients using pacemakers, 9. Individuals with epilepsy and neurological disorders, 10. Patients with habits such as alcohol and drug addiction, 11. Patients with advanced periodontitis, 12. Patients undergoing orthodontic treatment and having unstable occlusions, 13. Patients who have received radiotherapy and those taking medications that may cause MRI.

Key Trial Info

Start Date :

November 11 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06610383

Start Date

November 11 2021

End Date

November 1 2023

Last Update

September 24 2024

Active Locations (1)

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Afyonkarahisar Health Sciences University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

Afyonkarahisar, Afyonkarahisar, Turkey (Türkiye), 03030