Status:

RECRUITING

Effects of E-cigarette Use on Health

Lead Sponsor:

University of Wisconsin, Madison

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Electronic Cigarette Use

Eligibility:

All Genders

21+ years

Brief Summary

Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however their long-term health effects are unknown. This research proposal will quantify the effects of long-term ENDS us...

Detailed Description

Electronic nicotine delivery systems (ENDS) are used by millions of Americans, however, their long-term health effects are unknown. Although ENDS use delivers far lower levels of carcinogens than toba...

Eligibility Criteria

Inclusion

  • greater than or equal to 21 years of age
  • has vaped a nicotine e-cigarette product at least 2 days/week for most weeks for greater than or equal to 12 months
  • plans to remain in catchment area for greater than or equal to 3 years
  • smoked 5 or fewer tobacco cigarettes in the past 6 months
  • no serious CV, pulmonary, or other medical problems
  • not currently pregnant
  • no plans to stop vaping

Exclusion

  • serious CV, pulmonary, or other medical problems (e.g., moderate or severe aortic stenosis, class III or IV heart failure, blood pressure greater than or equal to 160/100 mmHg, interstitial lung disease, sarcoidosis, Stage 3 or 4 cancer)
  • combusted or vaped cannabis use 3 days/week or more in the past 3 months
  • currently pregnant
  • not able to read an write English
  • incarceration

Key Trial Info

Start Date :

January 6 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2029

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT06610838

Start Date

January 6 2025

End Date

June 30 2029

Last Update

December 24 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UW Center for Tobacco Research and Intervention

Madison, Wisconsin, United States, 53711