Status:

NOT_YET_RECRUITING

Intestinal Microbiota and Visceral Pain in Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO)

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Conditions:

Intestinal Obstruction

Eligibility:

All Genders

1-21 years

Brief Summary

Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO) is a rare gastrointestinal motility disorder. CIPO evolves through iterative flare-ups that can be triggered by viral or bacterial infections, psy...

Detailed Description

The aim of the study is to identify metabolites differentially produced by the gut microbiota of CIPO patients with visceral pain to determine their effect on the host with a focus on intestinal homeo...

Eligibility Criteria

Inclusion

  • Patient aged 1 to 21 years
  • Patient diagnosed with CIPO for at least 12 months (= patients meeting at least 2 of the following 4 criteria: 1. Recurrent episodes of intestinal dilatation, 2. Inability to maintain nutrition, 3. Intestinal neuromuscular alteration and 4. Genetic variants.)
  • Patient with an ileal or colonic digestive diversion
  • Signature of informed consent by both holders of parental authority and agreement in principle given orally by the subject;
  • Patients affiliated to a social security scheme

Exclusion

  • \-

Key Trial Info

Start Date :

October 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT06610929

Start Date

October 1 2024

End Date

November 1 2025

Last Update

September 26 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Robert Debre Hospital

Paris, France, 75019

Intestinal Microbiota and Visceral Pain in Chronic Intestinal Pseudo-Obstruction Syndrome (CIPO) | DecenTrialz