Status:
COMPLETED
MicroRNA Profile As a Biomarker of Liver Damage in Different Types of Liver Donors.
Lead Sponsor:
Mar Dalmau
Collaborating Sponsors:
Vall Hebron Insitut Recerca
Conditions:
MicroRNA Profile
Liver Transplant
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational study is to analyze the expression of liver-derived miRNAs in different types of liver donors to gain in depth knowledge about distinctive physiologic features within do...
Detailed Description
Between October 2019 and May 2021, perfusates, liver biopsies and serum samples were collected prospectively from adult deceased organ donors in Vall d\'Hebron University Hospital, Barcelona, Spai...
Eligibility Criteria
Inclusion
- I) Main donor groups (DBD and DCD):
- Adult deceased liver donors
Exclusion
- Pediatric donors (less than18 year-old)
- Donors for re-transplantation cases
- Donors who underwent split or partition liver technique to obtain two small grafts for two recipients (adult and pediatric).
- II) Discarded DBD grafts:
- Inclusion Criteria:
- \- Unusable grafts for transplantation due to moderate (30% to 60%) or severe (more than 60%) steatosis in liver biopsies.
Key Trial Info
Start Date :
October 2 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2024
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT06611046
Start Date
October 2 2019
End Date
September 1 2024
Last Update
September 24 2024
Active Locations (1)
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1
Vall d Hebron University Hospital
Barcelona, Barcelona, Spain, 08035