Status:

ACTIVE_NOT_RECRUITING

The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and Albuminuria

Lead Sponsor:

Attikon Hospital

Conditions:

Urine Albumin (UAlb)

Glycocalyx

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Patients with Type 2 Diabetes Mellitus and albuminuria will be randomised eitheer to dulaglutide and dapagliflozin combination or DPP-4 inhibitor, as an add-on treatment to metformin. Arterial stiffne...

Detailed Description

Patients with Type 2 Diabetes Mellitus and albuminuria will be randomised eitheer to dulaglutide and dapagliflozin combination or DPP-4 inhibitor, as an add-on treatment to metformin. Arterial stiffne...

Eligibility Criteria

Inclusion

  • Type 2 diabetes mellitus Albuminuria HbA1c: 7-10% eGFR\> 60 ml/min

Exclusion

  • Type 1 diabetes mellitus Inflammation, chronic or acute Established cardiovascular disease Malignancy within the last 5 years

Key Trial Info

Start Date :

February 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT06611904

Start Date

February 1 2018

End Date

December 15 2024

Last Update

September 25 2024

Active Locations (1)

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1

Attikon University General Hospital

Chaïdári, Attica, Greece, 12462