Status:

RECRUITING

Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions

Lead Sponsor:

Centre Francois Baclesse

Conditions:

Undifferentiated Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

The study is based on the constitution of a collection of tumor and blood samples for the development of tumoroid for functional tests to predict clinical response to treatment.

Eligibility Criteria

Inclusion

  • Patient with undifferentiated primary carcinoma (UPC) with histological and immunohistochemical evidence, validated in a local and/or national UPC multidisciplinary consultation
  • Patient with indication for systemic 1st-line treatment at the time of inclusion. Treatment may already have begun at the time of inclusion, but within the limit of 2 treatment cycles administered.
  • Patient with life expectancy greater than 3 months
  • Patient of legal age
  • Patient affiliated to a social security scheme
  • Signature of informed consent prior to any specific study procedure

Exclusion

  • Persons deprived of their liberty or under guardianship (including curatorship)
  • Pregnant or breast-feeding patient

Key Trial Info

Start Date :

March 5 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 15 2032

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06612827

Start Date

March 5 2025

End Date

December 15 2032

Last Update

December 24 2025

Active Locations (1)

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1

Centre François Baclesse

Caen, France