Status:

RECRUITING

A Dual-targeting Tracer TATE-RGD for the Diagnosis of SSTR- and RGD- Positive Tumors

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Iodine-resistant Thyroid Cancer

Meningioma

Eligibility:

All Genders

18-90 years

Phase:

EARLY_PHASE1

Brief Summary

The US FDA approved a targeted somatostatin receptor 2 imaging agent, 68Ga-DOTATATE, in 2016. It has higher uptake in small cell lung cancer, pulmonary carcinoid, and medullary thyroid cancer. Integri...

Detailed Description

This research has conducted extensive studies on the treatment of neuroendocrine tumors with 177Lu-EB-TATE and the treatment of FAP-expressing tumors with 177Lu-EB-FAPI. The same protocol had demonstr...

Eligibility Criteria

Inclusion

  • histologically confirmed various cancer patients;
  • 68Ga-TATE-RGD and 18F-FDG PET/CT within a week;
  • signed written consent.

Exclusion

  • known allergy against TATE-RGD;
  • any medical condition that in the opinion of the investigator may significantly interfere with study compliance.

Key Trial Info

Start Date :

August 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06632860

Start Date

August 1 2024

End Date

December 30 2025

Last Update

July 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 010100