Status:
RECRUITING
CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools
Lead Sponsor:
The Hospital for Sick Children
Conditions:
SARS CoV 2 Infection
RSV Infection
Eligibility:
All Genders
1+ years
Brief Summary
Viral respiratory tract infections are very common in children. They contribute to missed time in school, work disruption for caregivers and can also cause severe illness requiring hospitalization and...
Eligibility Criteria
Inclusion Criteria:
Viral dynamics (primary outcome):
- The child must be less than 18 years of age
- Have a positive PCR sample for influenza, RSV or SARS-CoV-2,
- Have any one of the symptoms listed to meet testing eligibility: fever, cough, shortness of breath, decreased or loss of taste or smell, muscle aches/joint pains (unusual, long lasting, not related to injury), extreme tiredness (unusual fatigue not otherwise explained), sore throat, runny or stuffy/congested nose, headache (new, unusual, long-lasting), nausea/vomiting and/or diarrhea, and
- Be within 5 days of symptom onset
Household testing inclusion criteria (secondary outcome):
-Any individual in the same household (i.e. household contacts, defined as residing at the same address) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis
Classroom testing inclusion criteria (secondary outcome):
-Any individual in the same classroom (i.e. classroom contacts) as the individual testing positive by PCR for influenza, RSV, SARS-CoV-2, mycoplasma pneumoniae, or bordetella pertussis (i.e. case identified through the THS program)
Exclusion Criteria:
Viral dynamics (primary outcome):
-Participants will be ineligible if they are more than 5 days from symptom onset
Key Trial Info
Start Date :
October 10 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT06640387
Start Date
October 10 2024
End Date
December 31 2026
Last Update
November 26 2025
Active Locations (1)
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1
The Hospital for Sick Children (SickKids)
Toronto, Ontario, Canada, M5G 1X8