Status:
RECRUITING
Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
Lead Sponsor:
Nest Genomics
Collaborating Sponsors:
Dana-Farber Cancer Institute
National Human Genome Research Institute (NHGRI)
Conditions:
Hereditary Cancer Syndromes
Clinical Decision Support
Eligibility:
All Genders
18-49 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to see if a software platform can improve cancer screening in young adults with genetic risk for cancer. The trial will also help improve the software platform (Nes...
Detailed Description
The overall objective of this project is to refine and study Nest, a software platform that integrates genetic data into patient care, with a goal of improving adherence to recommended care and empowe...
Eligibility Criteria
Inclusion Criteria:
- Ages 18-49 years, inclusive
- previous cancer genetic testing with a finding of a pathogenic or likely pathogenic variant resulting in an increased risk of cancer warranting clinical management.
- English-speaking and -reading
- Receiving care at Dana Farber Cancer Institute
- Not in active cancer therapy at the time of approach
Exclusion Criteria:
- Age <18 or >49 years
- Has not had genetic testing for hereditary cancer syndromes or has been tested but no pathogenic or likely pathogenic variant was identified.
- Non-English speaking and reading
- Not receiving care at Dana Farber Cancer Institute
- Active cancer with therapy in progress
Key Trial Info
Start Date :
February 10 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06654466
Start Date
February 10 2026
End Date
September 1 2027
Last Update
February 25 2026
Active Locations (1)
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1
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215