Status:

RECRUITING

A Multifocal TDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia

Lead Sponsor:

University of Campania Luigi Vanvitelli

Conditions:

Mild Cognitive Impairment (MCI)

Dementia

Eligibility:

All Genders

55-85 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to learn if an integrated protocol using multifocal non invasive brain stimulation and brain recording combined with cognitive training is effective in treating cogn...

Detailed Description

The global prevalence of dementia is expected to continue to rise. Recent estimates forecast that the number of people with dementia worldwide will increase to 152 million cases in 2050. This calls fo...

Eligibility Criteria

Inclusion Criteria:

  • age between 55 and 85 years;
  • diagnosis of minor neurocognitive disorder, or major neurocognitive disorder with mild severity, according to Diagnostic and Statistical Manual of Mental Disorders (DSM-5; APA 2013) with a Clinical Dementia Rating Scale (CDR) of .05 or 1 (Morris, 1993);
  • right handedness.

Exclusion Criteria:

  • brain events with an acute aetiology (stroke, traumatic brain injury, neoplastic ablation);
  • psychiatric disorders (schizophrenia, psychosis, bipolar disorder) and assumption of psychotropic drugs;
  • diagnosis of moderate or severe major neurocognitive disorders (DSM-5; APA 2013) with CDR scores equal or above 2 (Morris, 1993);
  • any condition with may also hypothetically interfere with electrophysiological recording and neurostimulation (metallic implants in the brain, cochlear implant, pacemakers, or suffering from epilepsy) (Antal et al., 2017; Bikson et al., 2016).

Key Trial Info

Start Date :

October 1 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06668610

Start Date

October 1 2024

End Date

October 1 2026

Last Update

October 31 2024

Active Locations (1)

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Department of Psychology, University of Campania "Luigi Vanvitelli"

Caserta, Italy, Italy, 81100