Status:
RECRUITING
Cannabis Observations on Brain Waves, Retrieval, and Attention: Experiment 3
Lead Sponsor:
L. Cinnamon Bidwell
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Cannabis
Memory
Eligibility:
All Genders
21-40 years
Brief Summary
This study investigates the impact of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) on recognition memory in healthy, regular cannabis users. Participants complete the same recognition memory ta...
Detailed Description
Previous research has established cannabis's harmful cognitive impact, with particularly robust and consistent effects in the domain of episodic memory. However, prior work has not sufficiently consid...
Eligibility Criteria
Inclusion Criteria:
- Must be between the ages of 21 and 40 and provide informed consent;
- Must be right-handed (Laterality Quotient > 60 on Edinburgh Handedness Inventory - Short Form);
- Must use cannabis at least 4 days during the month;
- Must be a cannabis user for at least a year;
- Must self-report not using other illicit recreational drugs (e.g., cocaine, benzodiazepines (non-prescription), opiates (non-prescription), MDMA, sedatives, or methamphetamine) in the past 30 days, during the Pre-Screening;
- Must not test positive on a urine toxicology test for drugs of abuse at the Baseline appointment;
- Must not be using psychotropic medications, however anti-depressant, non-benzodiazepine anti-anxiety, and ADHD medications are ok. ADHD medication users must be willing to abstain from ADHD medication use on appointment days;
- Must not be a regular nicotine user (≤4 days per week; cigarette, E-cigs, or smokeless);
- Must not have used caffeine or nicotine (cigarette, E-cigs, or smokeless) for 4 hours before each appointment;
- Must have a breath alcohol level of 0 at Baseline appointment (to sign consent form);
- Must not be actively seeking or in treatment for any substance use disorder;
- Female subjects must not be or trying to become pregnant (as indicated by a pregnancy test administered at Baseline appointment);
- Must not be in treatment for psychotic disorder or bipolar disorder; or have a history with these disorders;
- Must not have any physical characteristics (e.g., thick hair, head size exceeding the limit of the net, dyed hair) or experience any technical difficulties during testing that result in a poor-quality EEG recording.
Key Trial Info
Start Date :
October 9 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2026
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT06669585
Start Date
October 9 2024
End Date
January 1 2026
Last Update
December 9 2024
Active Locations (1)
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1
Center for Innovation and Creativity (CINC)
Boulder, Colorado, United States, 80301