Status:
RECRUITING
Ephedrine for Reducing Onset Time of Rocurinium in Elderly Patients
Lead Sponsor:
Matias Vested
Conditions:
Neuromuscular Blockade
Eligibility:
All Genders
80+ years
Phase:
PHASE4
Brief Summary
The aim of this study is to determine the onset time of rocuronium after administration of ephedrine 0.15 mg/kg in patients with age ≥ 80 years. The hypothesis of this study is that ephedrine 0.15 mg/...
Detailed Description
Numbers of elderly patients requiring anesthesia and surgery are increasing, and as a group, elderly patients are at high risk of postoperative complications. Aging leads to a progressive impairment o...
Eligibility Criteria
Inclusion Criteria:
- Age ≥ 80
- Scheduled for elective operations under general anesthesia with intubation
- American Society of Anesthesiologists physical status classification (ASA) I to III
- Informed consent
- Read and understand Danish
Exclusion Criteria:
- Known allergy to rocuronium or ephedrine
- Neuromuscular disease that may interfere with neuromuscular data
- Indication for rapid sequence induction
- Daily use of beta-blocking agents
- Known cardiac arrythmia (atrial fibrillation, supraventricular or ventricular)
Key Trial Info
Start Date :
January 13 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06681662
Start Date
January 13 2025
End Date
December 1 2025
Last Update
January 17 2025
Active Locations (2)
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1
Department of Anaesthesiology, Pain and Respiratory Support, Rigshospitalet Glostrup
Copenhagen, Denmark, 2100
2
Department of Anesthesia, Centre of Head and Orthopedics, 6013 Rigshospitalet
Copenhagen, Denmark, 2100