Status:

RECRUITING

Cavo-Tricuspid Isthmus Block Durability After Pulsed Electric Field Ablation

Lead Sponsor:

Institute for Clinical and Experimental Medicine

Conditions:

Flutter, Atrial

Cavotricuspid Isthmus Dependent Right Atrial Flutter

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study seeks to assess the acute durability of the CTI block when PEF energy is used. Second goal is to establish the optimal waiting time for the conduction recovery after PEF CTI ablation and to...

Detailed Description

Background Cavo-tricuspid isthmus (CTI) ablation is commonly performed as a concomitant procedure in patients undergoing pulmonary vein isolation (PVI) or more extensive left atrial ablations for the ...

Eligibility Criteria

Inclusion Criteria:

  • patients with paroxysmal AF undergoing PVI by PEF energy with documented typical atrial flutter or patients with persistent AF in whom catheter ablation of CTI is planned as a part of a complex procedure
  • Age ≥ 18 years at the time of study enrollment
  • Signed informed consent

Exclusion Criteria:

  • - LA diameter > 65 mm (measured in the parasternal long-axis view)
  • History of CTI ablation in the past
  • History of cardiac valve surgery
  • Significant valvular defect
  • Age below 18 years
  • Pregnancy, breastfeeding
  • Any disease with a life expectancy <1 year
  • Uncorrected congenital heart disease or valvular obstruction
  • Active myocarditis
  • Untreated hypothyroidism or hyperthyroidism
  • Recipient of any major organ transplant (e.g., lung, liver, heart)
  • HIV positivity with a survival expectancy of less than five years due to HIV
  • Chronic dialysis treatment
  • Unwillingness to participate.

Key Trial Info

Start Date :

September 16 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT06691074

Start Date

September 16 2024

End Date

December 31 2025

Last Update

November 15 2024

Active Locations (1)

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1

Institute for Clinical and Experimental Medicine

Prague, Prague, Czechia, 14200

Cavo-Tricuspid Isthmus Block Durability After Pulsed Electric Field Ablation | DecenTrialz