Inclusion Criteria:

• Male or female (balanced sex ratio or at least 40% male to 60% female) in complete autonomy at home.
• 55 to 75 years old, including the limits
• 20 ≤ BMI ≤35 kg/m2
• Available to carry out the entire protocol, including self-sampling (not sensitive to the sight of one's own blood for example) and agreeing to stop taking food supplements during the study.
• Having a scale available: at home, pharmacy, family, etc.
• Having internet access and a device with a screen and camera (PC, tablet, smartphone, etc.) at home or able to go to a project partner (CCAS, Point France Service, Community, Association, etc.) that can provide this access
• Subject agreeing to give written consent (by phone or videoconferencing), and registration in the national file of volunteers who participate in research
• Person declaring to be subject to a social security scheme.

Exclusion Criteria:

• Weight loss ≥ 5% in 1 month or ≥ 10% in 6 months or ≥ 10% compared to usual weight
• Treated diabetes
• Sub-acute pathology (flu, gastroenteritis, bacterial infection, etc.) or trauma (fracture, surgical intervention, etc.) in the 30 days prior to inclusion.
• Hepatocellular insufficiency,
• Heart failure with decompensation,
• Renal insufficiency (clearance <30 ml/min)
• Chronic anti-inflammatory treatment, long-term corticosteroid therapy > 1 month, infiltration
• Progressive pathology at the time of inclusion (cancer, etc.)
• Gastrointestinal pathology deemed incompatible with the protocol
• Unstable thyroid diseases
• Recent change in eating habits in the last 30 days (weight loss diet, veganism, intermittent fasting, ketogenic diet, etc.)
• Intense physical activity (activity causing shortness of breath and sweating) > 10 hours per week
• Person in a period of exclusion from the National File of Healthy Volunteers
• Subject under guardianship, curator-ship, deprived of liberty or under judicial protection