Status:

RECRUITING

Aerobic Exercise and Its Impact on Sensory, Musculoskeletal, and Psychosocial Aspects in Migraine

Lead Sponsor:

University of Sao Paulo

Conditions:

Migraine

Migraine Disease

Eligibility:

FEMALE

18-48 years

Phase:

NA

Brief Summary

Migraine is a neurological disorder associated with high levels of disability and changes in sensory processing, musculoskeletal function, and psychosocial factors. Aerobic exercise is a low-cost, non...

Detailed Description

Migraine is a complex neurological disorder characterized by sensory dysfunction, musculoskeletal alterations, and psychosocial impairments, often resulting in substantial disability. Although aerobic...

Eligibility Criteria

Inclusion Criteria:

  • Women aged between 18 and 48 years.
  • Diagnosed with migraine by an experienced neurologist specialized in headaches, following the criteria of the International Classification of Headache Disorders (ICHD).
  • Frequency of headache between 3 and 8 days per month, to ensure adherence to the treatment.

Exclusion Criteria:

  • Presence of any other type of concurrent headache.
  • Medical conditions affecting sensitivity and autonomic modulation, such as peripheral neuropathies, autonomic disorders, severe neurological diseases, and others.
  • Conditions that prevent physical activity, such as severe musculoskeletal injuries, cardiovascular diseases, or related conditions.
  • Premature ovarian failure.
  • Regular physical exercise in the past year.
  • Body Mass Index (BMI) above 30.0.
  • Smokers or individuals using drugs that interfere with sensitivity and cardiac modulation (e.g., beta-blockers).
  • Abuse of abortive medications.

Key Trial Info

Start Date :

March 3 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 30 2028

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06716489

Start Date

March 3 2026

End Date

November 30 2028

Last Update

February 5 2026

Active Locations (1)

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Ribeirão Preto Medical School - University of São Paulo (FMRP-USP)

Ribeirão Preto, São Paulo, Brazil, 14049-900