Status:

RECRUITING

A Study on Treatment for Patients With BRAFV600E Mutant Metastatic Colorectal Cancer (mCRC)

Lead Sponsor:

Fudan University

Conditions:

Metastatic Colorectal Cancer

BRAF V600 Mutation

Eligibility:

All Genders

18+ years

Brief Summary

Previous studies have shown that BRAFV600E mutant mCRC patients have a shorter survival time than BRAF wild type mCRC patients. For Chinese patients, however, it remains unclear about the BRAF gene mu...

Eligibility Criteria

Inclusion Criteria:

  • Diagnosis of histologically or cytologically confirmed CRC that is metastatic and unresectable
  • Presence of BRAFV600E mutation in tumor tissue, as confirmed by a local assay

Exclusion Criteria:

  • patients with previous chronic inflammatory bowel disease, chronic diarrhea or recurrent bowel obstruction patients with symptomatic brain metastases active clinical severe infection

Key Trial Info

Start Date :

March 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06749015

Start Date

March 1 2021

End Date

October 1 2026

Last Update

December 27 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China, 200032