Status:
RECRUITING
AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction
Lead Sponsor:
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Conditions:
Unruptured Cerebral Aneurysm
Artificial Intelligence (AI)
Eligibility:
All Genders
18+ years
Brief Summary
Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%. Early diagnosis and intervention b...
Eligibility Criteria
Inclusion Criteria:
- Age ≥ 18 years;
- Preliminary diagnosis or symptoms indicating the presence or potential presence of a cerebral aneurysm;
- Undergoing a non-contrast head MRA or contrast-enhanced head/neck CTA;
- The patient or their legal representative is able and willing to sign an informed consent form.
Exclusion Criteria:
- Other intracranial vascular diseases: moyamoya disease, arteriovenous malformations, arteriovenous fistulas, arterial occlusions, and arterial dissections;
- History of intracranial arterial interventions: stent placement, partial aneurysm coil treatment, etc.;
- Severe allergy to contrast agents or absolute contraindications to iodine-based contrast agents;
- Renal insufficiency with elevated serum creatinine (greater than twice the upper normal limit);
- MRI contraindications: pacemakers, claustrophobia, etc.;
- Diseases or conditions that affect the quality of CTA/MRA images;
- Inability to complete the study due to psychiatric disorders, cognitive, or emotional disturbances.
Note: The CTA sub-study does not include exclusion criterion 5; the MRA sub-study does not include exclusion criteria 3 and 4.
Key Trial Info
Start Date :
January 10 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2027
Estimated Enrollment :
10000 Patients enrolled
Trial Details
Trial ID
NCT06766422
Start Date
January 10 2025
End Date
June 30 2027
Last Update
June 3 2025
Active Locations (1)
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1
Shanghai Sixth People's Hospital, Shanghai, 200023
Shanghai, China