Status:

RECRUITING

AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction

Lead Sponsor:

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

Conditions:

Unruptured Cerebral Aneurysm

Artificial Intelligence (AI)

Eligibility:

All Genders

18+ years

Brief Summary

Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%. Early diagnosis and intervention b...

Eligibility Criteria

Inclusion Criteria:

  1. Age ≥ 18 years;
  2. Preliminary diagnosis or symptoms indicating the presence or potential presence of a cerebral aneurysm;
  3. Undergoing a non-contrast head MRA or contrast-enhanced head/neck CTA;
  4. The patient or their legal representative is able and willing to sign an informed consent form.

Exclusion Criteria:

  1. Other intracranial vascular diseases: moyamoya disease, arteriovenous malformations, arteriovenous fistulas, arterial occlusions, and arterial dissections;
  2. History of intracranial arterial interventions: stent placement, partial aneurysm coil treatment, etc.;
  3. Severe allergy to contrast agents or absolute contraindications to iodine-based contrast agents;
  4. Renal insufficiency with elevated serum creatinine (greater than twice the upper normal limit);
  5. MRI contraindications: pacemakers, claustrophobia, etc.;
  6. Diseases or conditions that affect the quality of CTA/MRA images;
  7. Inability to complete the study due to psychiatric disorders, cognitive, or emotional disturbances.

Note: The CTA sub-study does not include exclusion criterion 5; the MRA sub-study does not include exclusion criteria 3 and 4.

Key Trial Info

Start Date :

January 10 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2027

Estimated Enrollment :

10000 Patients enrolled

Trial Details

Trial ID

NCT06766422

Start Date

January 10 2025

End Date

June 30 2027

Last Update

June 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Shanghai Sixth People's Hospital, Shanghai, 200023

Shanghai, China