Status:

RECRUITING

A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis

Lead Sponsor:

University of Birmingham

Collaborating Sponsors:

Christian Medical College and Hospital, Ludhiana, India

Ministry of Health, Ghana

Conditions:

Appendicitis

Appendectomy

Eligibility:

All Genders

Brief Summary

This study aims to assess and improve the global management of appendicitis, the most common emergency surgery, by examining various aspects of emergency care systems worldwide. Appendicitis is a time...

Detailed Description

This prospective, multicentre, global cohort study will capture patients within an overall study window of 3 February 2025 to 25 May 2025. Any hospital performing appendicectomy worldwide will be elig...

Eligibility Criteria

Inclusion Criteria:

  • Age: There are no age restrictions, although, if appropriate participating hospitals can choose to only include children or only adults, based on an age cut-off of their choice.
  • Procedure: All patients undergoing appendicectomy for suspected or confirmed appendicitis by any surgical approach should be included. This includes patients who went theatre with suspect appendicitis even if the intraoperative or pathology results found a different diagnosis, so long as an appendicectomy was performed. It also includes patients who went to theatre for reasons other than suspected appendicitis but were found to have appendicitis intraoperatively and underwent appendicectomy. This includes interval appendicectomy and right hemicolectomy if performed for acute appendicitis.
  • Approach: Both open and minimally invasive (laparoscopic and robotic) interventions are eligible for inclusion. Laparoscopic and robotic converted to open cases are also eligible.

Exclusion Criteria:

  • Indication: Appendicectomy for any indication other than suspected or confirmed appendicitis should be excluded. For example, patients having appendicectomy for known appendiceal neoplasm.
  • Procedure: Patients having appendectomy as part of another surgical procedure should be excluded. For example, patients having removal of appendix as part of a colon cancer procedure are not eligible for inclusion.
  • Approach: Natural orifice surgery and endoscopic treatment for suspected appendicitis are excluded.
  • Previous appendicectomy: Patients having surgery for stump appendicitis are excluded.
  • Return to theatre: Patients should be entered into study only once. A patient returning to theatre after appendectomy should not be re-entered as a new patient.

Key Trial Info

Start Date :

February 3 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

14000 Patients enrolled

Trial Details

Trial ID

NCT06774001

Start Date

February 3 2025

End Date

December 1 2025

Last Update

April 2 2025

Active Locations (7)

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Page 1 of 2 (7 locations)

1

University of Abomey Calavi

Cotonou, Benin

2

Tamale Teaching Hospital

Tamale, Ghana

3

Christian Medical College and Hospital Ludhiana

Ludhiana, India

4

Hospital Espanol Veracruz

Veraruz, Mexico

A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis | DecenTrialz