Status:
RECRUITING
A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis
Lead Sponsor:
University of Birmingham
Collaborating Sponsors:
Christian Medical College and Hospital, Ludhiana, India
Ministry of Health, Ghana
Conditions:
Appendicitis
Appendectomy
Eligibility:
All Genders
Brief Summary
This study aims to assess and improve the global management of appendicitis, the most common emergency surgery, by examining various aspects of emergency care systems worldwide. Appendicitis is a time...
Detailed Description
This prospective, multicentre, global cohort study will capture patients within an overall study window of 3 February 2025 to 25 May 2025. Any hospital performing appendicectomy worldwide will be elig...
Eligibility Criteria
Inclusion Criteria:
- Age: There are no age restrictions, although, if appropriate participating hospitals can choose to only include children or only adults, based on an age cut-off of their choice.
- Procedure: All patients undergoing appendicectomy for suspected or confirmed appendicitis by any surgical approach should be included. This includes patients who went theatre with suspect appendicitis even if the intraoperative or pathology results found a different diagnosis, so long as an appendicectomy was performed. It also includes patients who went to theatre for reasons other than suspected appendicitis but were found to have appendicitis intraoperatively and underwent appendicectomy. This includes interval appendicectomy and right hemicolectomy if performed for acute appendicitis.
- Approach: Both open and minimally invasive (laparoscopic and robotic) interventions are eligible for inclusion. Laparoscopic and robotic converted to open cases are also eligible.
Exclusion Criteria:
- Indication: Appendicectomy for any indication other than suspected or confirmed appendicitis should be excluded. For example, patients having appendicectomy for known appendiceal neoplasm.
- Procedure: Patients having appendectomy as part of another surgical procedure should be excluded. For example, patients having removal of appendix as part of a colon cancer procedure are not eligible for inclusion.
- Approach: Natural orifice surgery and endoscopic treatment for suspected appendicitis are excluded.
- Previous appendicectomy: Patients having surgery for stump appendicitis are excluded.
- Return to theatre: Patients should be entered into study only once. A patient returning to theatre after appendectomy should not be re-entered as a new patient.
Key Trial Info
Start Date :
February 3 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
14000 Patients enrolled
Trial Details
Trial ID
NCT06774001
Start Date
February 3 2025
End Date
December 1 2025
Last Update
April 2 2025
Active Locations (7)
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1
University of Abomey Calavi
Cotonou, Benin
2
Tamale Teaching Hospital
Tamale, Ghana
3
Christian Medical College and Hospital Ludhiana
Ludhiana, India
4
Hospital Espanol Veracruz
Veraruz, Mexico