Status:

RECRUITING

Autophagy/Apoptosis Balance in Placental Vascular Pathologies

Lead Sponsor:

Centre Hospitalier Universitaire de Nīmes

Conditions:

Pregnancy Complications

Pre-Eclampsia

Eligibility:

FEMALE

18+ years

Brief Summary

Pregnancy increases the risk of thrombosis. Placenta-mediated diseases are a risk factor for cardiovascular pathologies and can lead to maternal-fetal morbidity and mortality. It is essential to under...

Detailed Description

Pregnancy increases the risk of thrombosis. Diseases mediated by the placenta are a risk factor for cardiovascular pathologies. They are responsible for significant maternal-fetal morbidity and mortal...

Eligibility Criteria

Inclusion Criteria:

  • Pregnant women developing a placental vascular complication (preeclampsia and/or intrauterine growth retardation), hospitalized and delivering at Nimes University Hospital.
  • Pregnant woman with free and informed consent.
  • Pregnant woman affiliated with and/or benefiting from a health insurance scheme.

Exclusion criteria:

  • Multiple pregnancy.
  • Presence of hypertension and/or proteinuria prior to pregnancy.
  • Participant in an interventional drug study.
  • Persons in a period of exclusion determined by another study.
  • Persons under court protection, guardianship or curatorship.
  • Persons unable to give consent.
  • Persons for whom it is impossible to give informed information.

Key Trial Info

Start Date :

May 2 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2027

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT06779916

Start Date

May 2 2025

End Date

May 1 2027

Last Update

November 17 2025

Active Locations (1)

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Nimes University Hospital

Nîmes, France