Inclusion Criteria:

• Conforming to the diagnostic criteria of AMN, with a definite genetic testing report, and complicated by lower limb motor function disorders;
• Capable of normal communication and able to complete scale tests independently (as determined by on-site scale tests);
• Willing to participate in this study after giving informed consent;
• The muscle tone of the patient's bilateral lower extremities was elevated.

Exclusion Criteria:

• Other inherited diseases;
• Other severe central nervous system diseases;
• History of brain surgery;
• Psychiatric and psychological diseases such as depression and anxiety;
• The presence of metallic foreign bodies or prostheses (such as cardiac pacemakers, insulin pumps) in the body, claustrophobia, and other contraindications for MRI;
• Informed consent was not obtained;
• Unable to tolerate MRI-related examinations;
• Received anticoagulant, antispasmodic or antiepileptic drug therapies throughout the entire study period;
• Postoperative wound infection;
• Other motor disorders, spinal cord pathologies, fractures, osteoarthritis, amputations, scoliosis and other movement-affecting diseases.