Status:

RECRUITING

Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma

Lead Sponsor:

West China Hospital

Conditions:

Infantile Hemangioma

Eligibility:

All Genders

1-4 years

Phase:

PHASE2

PHASE3

Brief Summary

The main objective of this study was to determine the efficacy of different doses of propranolol in the treatment of ulcerattion infantile hemangioma (IH).

Detailed Description

Infantile hemangioma (IH) is the most common benign tumor in infants, with an estimated prevalence of 4%-5%. Although most IH resolves over time without serious sequelae, a significant proportion can ...

Eligibility Criteria

Inclusion Criteria:

  1. all patients with ulcer IH;
  2. children with ulcer IH treated with propranolol.

Exclusion Criteria:

1) children with ulcer IH who received other therapeutic interventions were excluded; 2) Children whose families refused to participate in the study; 3) patients with contraindications to oral propranolol, such as allergy to propranolol, severe bradycardia and bronchial asthma; 4) children lost to follow-up during oral propranolol treatment; 5) children unable to oral propranolol or continue to oral propranolol due to other reasons.

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Key Trial Info

Start Date :

May 2 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06798363

Start Date

May 2 2025

End Date

August 1 2026

Last Update

March 16 2026

Active Locations (1)

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1

West China Hospital of Sichuan University

Chengdu, Sichuan, China, 610041