Inclusion Criteria:

• 50 - 84 years of age at the time of enrolment (within year of birth, not month of birth)
• Haemoglobin A1c (HbA1c) ≥ 48 or 6.5% and/or confirmed type II DM diagnosed within the last 180 days (+20 days flexibility allowance)
• Willing to provide up to 30 mL of blood for each study visit
• Willing and eligible to undergo MRI scan (or CT scan if MRI is contraindicated)
• Understands the study process and is willing to take part in the study and sign the informed consent form

Exclusion Criteria:

• Prior type I or type II DM diagnosis > 6 months
• A history of pancreatic cancer, pancreatic neuroendocrine tumour (pNET) or Pancreatitis
• Under investigation for pancreatic cancer / pancreatic cyst
• Any known pancreatic surgery (not including ERCP), or other major surgery requiring anaesthesia within 3 months
• Any invasive solid or haematological cancer in the past 3 years, including cancer recurrence after treatment in the last 3 years
• Current chronic or acute oral or systemic steroid use within 3 months of initial HbA1c or diabetes diagnosis (estimate rather than accurate)
• Blood transfusion within 1 month
• Solid organ transplant recipient
• Currently pregnant
• Needing dialysis