Status:

RECRUITING

Analysis of Influencing Factors of High-Order Aberrations of SMILE with Lenticule Retained

Lead Sponsor:

Second Affiliated Hospital of Nanchang University

Conditions:

Small-incision Lenticule Extraction (SMILE) Surgery

Corneal Higher-order Wavefront Aberrations

Eligibility:

All Genders

18-45 years

Brief Summary

Analysis of Influencing Factors of High-Order Aberrations of SMILE with Lenticule Retained

Detailed Description

Wavefront analysis and other objective methods are the mainstream approaches for assessing visual quality after refractive surgery, with high-order aberrations being the main observation indicators. S...

Eligibility Criteria

Inclusion Criteria:

  1. Age ≥ 18 years, gender unrestricted;
  2. Equivalent spherical refraction ≤ -10.0D, corrected distance visual acuity ≥ 1.0, myopia stable for ≥ 2 years, and no contact lens wear for at least 2 weeks;
  3. The patient voluntarily participates in this study, signs the informed consent form, and agrees to follow up according to the study plan;
  4. Predicted postoperative residual corneal stromal thickness ≥ 280 micrometers.

Exclusion Criteria:

  1. Subclinical keratoconus, keratoconus, moderate to severe corneal opacities or scars, and other ocular conditions;
  2. Diabetes, keloid-prone constitution, autoimmune and connective tissue diseases, etc.;
  3. Severe mental disorders such as generalized anxiety disorder, panic disorder, depression, schizophrenia, and bipolar disorder; inability to cooperate with physicians;
  4. Refusal to participate in the study.

Key Trial Info

Start Date :

October 31 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 31 2025

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT06806085

Start Date

October 31 2024

End Date

October 31 2025

Last Update

February 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China, 330000

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