Status:

RECRUITING

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Lead Sponsor:

AbbVie

Conditions:

Chronic Migraine

Eligibility:

All Genders

12-17 years

Phase:

PHASE3

Brief Summary

Migraine is a disease that most often causes moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to...

Eligibility Criteria

Inclusion Criteria:

  • History of chronic migraine with or without aura consistent with a diagnosis according to the International Classification of Headache Disorders, 3rd Edition (ICHD-3) (2018) for at least 6 months as of Visit 1.

  • During the last 28 days of the screening/baseline period, and as per eDiary:

    • Participant must have completed the eDiary for a minimum of 20 out of 28 days.
    • Participant has >= 15 headache days.
    • Participant has >= 8 migraine days.

Exclusion Criteria:

  • Clinically significant hypertension per investigator's judgment.
  • History of any clinically significant hematologic, endocrine, pulmonary, renal, hepatic, gastrointestinal, cardiovascular or neurologic disease.

Key Trial Info

Start Date :

February 13 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2031

Estimated Enrollment :

420 Patients enrolled

Trial Details

Trial ID

NCT06810505

Start Date

February 13 2025

End Date

March 1 2031

Last Update

April 14 2026

Active Locations (61)

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Page 1 of 16 (61 locations)

1

Rehabilitation & Neurological Services /ID# 270782

Huntsville, Alabama, United States, 35805

2

Preferred Research Partner, Inc /ID# 270389

Little Rock, Arkansas, United States, 72211

3

Preferred Research Partners /ID# 270419

Little Rock, Arkansas, United States, 72211

4

Advanced Research Center /ID# 270257

Anaheim, California, United States, 92805

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years | DecenTrialz