Status:

RECRUITING

7T Anatomo-functional Characterization of Structures in the Action Observation Network

Lead Sponsor:

IRCCS Fondazione Stella Maris

Collaborating Sponsors:

University of Parma

Fondazione IMAGO7

Conditions:

Brain Function

Cerebral Palsy

Eligibility:

All Genders

11-40 years

Brief Summary

The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical conne...

Detailed Description

In healthy humans, brain functional representation of actions, either executed or observed, relies on the human action observation network (AON). Several studies demonstrated that AON activation is cr...

Eligibility Criteria

For CP patients

Inclusion Criteria:

  • Patients with pre-, peri- or post-natal brain injury, documented by a previous MRI examination of the brain;
  • Intellectual development within the norm or within the mild deficit area, to guarantee understanding and cooperation in the 7T fMRI study;
  • Understanding of the Italian language;

Exclusion Criteria:

  • Contraindications to performing the 7T fMRI exam;
  • Neuropsychiatric comorbidity that precludes collaboration in the 7T fMRI study;
  • Lack of capacity to understand and to will;
  • Pregnancy;

For Healthy Controls

Inclusion Criteria:

  • Absence of known neurological and psychiatric pathologies;
  • Understanding of the Italian language;

Exclusion Criteria:

  • Contraindications to performing the 7T fMRI exam;
  • Neuropsychiatric comorbidity that precludes collaboration in the 7T fMRI study;
  • Lack of capacity to understand and to will;
  • Pregnancy;

Key Trial Info

Start Date :

December 2 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 9 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06826287

Start Date

December 2 2024

End Date

August 9 2025

Last Update

February 13 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Fondazione IMAGO7

Calambrone, PISA, Italy, 56018

2

IRCCS Fondazione Stella Maris

Calambrone, Pisa, Italy, 56018