Status:
RECRUITING
7T Anatomo-functional Characterization of Structures in the Action Observation Network
Lead Sponsor:
IRCCS Fondazione Stella Maris
Collaborating Sponsors:
University of Parma
Fondazione IMAGO7
Conditions:
Brain Function
Cerebral Palsy
Eligibility:
All Genders
11-40 years
Brief Summary
The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical conne...
Detailed Description
In healthy humans, brain functional representation of actions, either executed or observed, relies on the human action observation network (AON). Several studies demonstrated that AON activation is cr...
Eligibility Criteria
For CP patients
Inclusion Criteria:
- Patients with pre-, peri- or post-natal brain injury, documented by a previous MRI examination of the brain;
- Intellectual development within the norm or within the mild deficit area, to guarantee understanding and cooperation in the 7T fMRI study;
- Understanding of the Italian language;
Exclusion Criteria:
- Contraindications to performing the 7T fMRI exam;
- Neuropsychiatric comorbidity that precludes collaboration in the 7T fMRI study;
- Lack of capacity to understand and to will;
- Pregnancy;
For Healthy Controls
Inclusion Criteria:
- Absence of known neurological and psychiatric pathologies;
- Understanding of the Italian language;
Exclusion Criteria:
- Contraindications to performing the 7T fMRI exam;
- Neuropsychiatric comorbidity that precludes collaboration in the 7T fMRI study;
- Lack of capacity to understand and to will;
- Pregnancy;
Key Trial Info
Start Date :
December 2 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 9 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06826287
Start Date
December 2 2024
End Date
August 9 2025
Last Update
February 13 2025
Active Locations (2)
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1
Fondazione IMAGO7
Calambrone, PISA, Italy, 56018
2
IRCCS Fondazione Stella Maris
Calambrone, Pisa, Italy, 56018