Status:

NOT_YET_RECRUITING

Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD)

Lead Sponsor:

Oui Therapeutics, Inc.

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Florida State University

Conditions:

PTSD

Post Traumatic Stress Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.

Detailed Description

The purpose of this study is to conduct a randomized controlled trial to evaluate the usability and feasibility as well as the safety and effectiveness of OTX-601 (version 1) + TAU compared to OTX-601...

Eligibility Criteria

Inclusion

  • Posttraumatic stress disorder (PTSD) diagnosis
  • Anxiety Sensitivity Index 3 (ASI-3) scores above 24
  • PTSD Checklist for DSM-V (PCL-5) scores above 30
  • Understands and speaks English
  • Access to a smartphone that is connected to the internet

Exclusion

  • Score of 24 or lower on the ASI-3
  • Score of 30 and below on the PCL-5
  • No PTSD diagnosis
  • Active psychosis
  • Acute intoxication during study baseline
  • Enrolled in another treatment research study
  • Medical illness that would prevent the completion of interoceptive exposure exercises

Key Trial Info

Start Date :

June 30 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 30 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06868446

Start Date

June 30 2025

End Date

January 30 2026

Last Update

June 19 2025

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