Status:

ACTIVE_NOT_RECRUITING

Detection of Keratoconus Progression Using Machine Learning

Lead Sponsor:

Vienna Institute for Research in Ocular Surgery

Conditions:

Keratoconus

Machine Learning

Eligibility:

All Genders

Brief Summary

Keratoconus (KC) is a bilateral ocular disease characterized by progressive thinning and steepening of the cornea, usually in its inferotemporal region. The disease often occurs asymmetrically as one ...

Eligibility Criteria

Inclusion

  • Patients with KC progression as defined dependent on Kmax/year:
  • o
  • Kmax \< 48 Dioptres (D): \>0.5 D per year o
  • Kmax 48.01-53 D: \>0.6 D per year o
  • Kmax 53.01-58 D: \>0.8 D per year o
  • Kmax \> 58 D: \>1.5 D per year - Non progressive group: Patients with stable KC (KC progression dependent on Kmax \< than the values described above/year)

Exclusion

  • Relevant other ophthalmic diseases that are likely to influence the measurement outcome like corneal scars or epithelial dystrophies
  • Too few measurements/too short follow-up to define progression of KC

Key Trial Info

Start Date :

December 2 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2025

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06873399

Start Date

December 2 2024

End Date

May 1 2025

Last Update

March 12 2025

Active Locations (1)

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Vienna Institute for Research in Ocular Surgery (VIROS)

Vienna, Vienna, Austria, 1140