Status:

NOT_YET_RECRUITING

Non-Invasive Prediction of Necrotizing Enterocolitis in Preterm Neonates with Feeding Intolerance Using Fecal Lipocalin-2 and Electrical Cardiometry

Lead Sponsor:

Ain Shams University

Conditions:

Feeding Intolerance in Preterm

NEC

Eligibility:

All Genders

1-28 years

Brief Summary

Prospective observational study to evaluate the efficiency of using electrical cardiometry in combination with fecal lipocalin-2 for prediction of NEC in preterm neonates with feeding intolerance

Detailed Description

Necrotizing enterocolitis is one of the most life-threatening conditions for premature infants in neonatal intensive care units (NICU) and is associated with severe intestinal inflammation and necrosi...

Eligibility Criteria

Inclusion

  • Preterm neonates with gestational age ≤ 35 weeks, admitted to NICU, started enteral feeding and diagnosed as having feeding intolerance defined as stage IA and IB by modified bell's staging

Exclusion

  • Chromosomal anomaly or multiple congenital malformations.
  • Patient with surgical malformation of the intestinal tract (i.e. omphalocele, gastroschisis, malrotation, intestinal atresia)
  • Patient diagnosed as hypoxic ischemic encephalopathy.

Key Trial Info

Start Date :

March 5 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 5 2026

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06874153

Start Date

March 5 2025

End Date

June 5 2026

Last Update

March 13 2025

Active Locations (1)

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Faculty of medicine, Ain Shams university.

Cairo, Abbasia, Egypt, 11517