Status:
COMPLETED
Minimally Invasive Surgical Intervention for Hirschsprung's Disease in Pediatric Patients
Lead Sponsor:
National Children's Hospital, Vietnam
Conditions:
Hirschsprung Disease
Eligibility:
All Genders
Up to 18 years
Brief Summary
Hirschsprung's disease (HD) is a congenital disorder characterized by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates...
Detailed Description
Hirschsprung's disease (HD) is a congenital disorder caused by the absence of enteric ganglion cells in the distal bowel, leading to functional obstruction, delayed meconium passage in neonates, and d...
Eligibility Criteria
Inclusion
- All pediatric patients (under 18 years old) diagnosed with Hirschsprung's Disease, admitted to National Children's Hospital between January 2017 and December 2023.
- Patients exhibiting clinical signs and symptoms consistent with Hirschsprung's Disease, with imaging findings confirming the diagnosis. If imaging was inconclusive but clinical suspicion remained high, patients were still considered for surgical evaluation and management.
- Underwent minimally invasive laparoscopic pull-through surgery, either conventional multi-port (CLP) or single-incision (SILS).
- Postoperative Follow-up Data Availability: Patients with documented short-term postoperative outcomes, including bowel function recovery, complications, or reoperation rates.
Exclusion
- Clinical instability requiring emergency open laparotomy due to peritonitis, intestinal perforation, or other life-threatening conditions.
- Biopsy findings inconsistent with Hirschsprung's Disease, ruling out the diagnosis.
- Incomplete Medical Records: Patients with missing key data, such as operative details, pathology reports, or follow-up outcomes, that could compromise study integrity
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2025
Estimated Enrollment :
1050 Patients enrolled
Trial Details
Trial ID
NCT06874686
Start Date
January 1 2017
End Date
February 1 2025
Last Update
March 17 2025
Active Locations (1)
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1
Department of Surgery, The National Children Hospital, Hanoi
Hanoi, Vietnam